Resorufin

Names

[ CAS No. ]:
635-78-9

[ Name ]:
Resorufin

[Synonym ]:
7-hydroxy-phenoxazin-3-one
7-Hydroxy-phenoxazin-3-on
7-hydroxyphenoxazin-3-one
Resorufine
3H-Phenoxazin-3-one,7-hydroxy
7-Hydroxy-3H-phenoxazin-3-one
7-Hydroxy-3H-phenoxazine-3-one
MFCD00128991
EINECS 211-241-8
Resorufin

Biological Activity

[Description]:

Resorufin (NSC 12097) is a highly fluorescent pink dye.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Odyniec ML , et al. 'AND'-based fluorescence scaffold for the detection of ROS/RNS and a second analyte. Chem Commun (Camb). 2018 Jul 26;54(61):8466-8469.

Chemical & Physical Properties

[ Density]:
1.46 g/cm3

[ Boiling Point ]:
413ºC at 760 mmHg

[ Melting Point ]:
>300 °C(lit.)

[ Molecular Formula ]:
C₁₂H₇NO₃

[ Molecular Weight ]:
213.18900

[ Flash Point ]:
203.6ºC

[ Exact Mass ]:
213.04300

[ PSA ]:
63.33000

[ LogP ]:
1.99840

[ Storage condition ]:
?20°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SP7698000

CHEMICAL NAME :: 3H-Phenoxazin-3-one, 7-hydroxy-

CAS REGISTRY NUMBER :: 635-78-9

BEILSTEIN REFERENCE NO. :: 0174850

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H7-N-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,24,1953

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
SP7698000

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Membrane anchor of cytochrome P450 reductase suppresses the uncoupling of cytochrome P450.

Chem. Pharm. Bull. 63(4) , 286-94, (2015)

Cytochrome P450 reductase (CPR) is an important redox partner of microsomal CYPs. CPR is composed of a membrane anchor and a catalytic domain that contains FAD and flavin mononucleotide (FMN) as redox...

Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors.

ChemMedChem 10(2) , 253-65, (2015)

At present, inhibitors of α/β-hydrolase domain 6 (ABHD6) are viewed as a promising approach to treat inflammation and metabolic disorders. This article describes the development of 1,2,5-thiadiazole c...

Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts.

Biochim. Biophys. Acta 1842(12 Pt A) , 2468-78, (2014)

The cardiotoxicity induced by the anti-cancer doxorubicin involves increased oxidative stress, disruption of calcium homeostasis and activation of cardiomyocyte death. Nevertheless, antioxidants and c...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.