ANR 94

Names

[ Name ]:
ANR 94

[Synonym ]:
9H-Purin-6-amine,8-ethoxy-9-ethyl

Biological Activity

[Description]:

ANR94 is a potent and selective adenosine A2A receptor (AA2AR) antagonist with an Ki of 46 nM for hAA2AR. ANR94 has the potential for the research of Parkinson's disease[1][2].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor

[Target]

A2AR:46 nM (Ki, human)

[References]

[1]. Volpini R, et al. Adenosine A2A receptor antagonists: new 8-substituted 9-ethyladenines as tools for in vivo rat models of Parkinson's disease. ChemMedChem. 2009;4(6):1010-1019.

[2]. Micioni Di Bonaventura MV, et al. Regulation of adenosine A2A receptor gene expression in a model of binge eating in the amygdaloid complex of female rats. J Psychopharmacol. 2019;33(12):1550-1561.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₃N₅O

[ Molecular Weight ]:
207.23200

[ Exact Mass ]:
207.11200

[ PSA ]:
78.85000

[ LogP ]:
1.40830

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ RIDADR ]:
UN 2811 6.1 / PGIII

Related Compounds

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