Malabaricone C

Names

[ Name ]:
Malabaricone C

[Synonym ]:
1-(2,6-Dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)-1-nonanone
malabaricon C

Biological Activity

[Description]:

Malabaricone C is a natural sphingomyelin synthase (SMS) inhibitor with IC50s of 3 and 1.5 μM for SMS 1 and 2, respectively[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Othman MA, et al. Malabaricone C as Natural Sphingomyelin Synthase Inhibitor against Diet-Induced Obesity and Its Lipid Metabolism in Mice. ACS Med Chem Lett. 2019;10(8):1154-1158. Published 2019 Jul 3.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₆O₅

[ Molecular Weight ]:
358.42800

[ Exact Mass ]:
358.17800

[ PSA ]:
97.99000

[ LogP ]:
4.66510

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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