3-(5-Nitro-2-furyl)acrylic Acid
Names
[ CAS No. ]:
6281-23-8
[ Name ]:
3-(5-Nitro-2-furyl)acrylic Acid
[Synonym ]:
EINECS 228-488-2
MFCD00143078
3-(5-Nitro-2-furyl)acrylic acid
Chemical & Physical Properties
[ Boiling Point ]:
348.8ºC at 760 mmHg
[ Molecular Formula ]:
C7H5NO5
[ Molecular Weight ]:
183.11800
[ Flash Point ]:
164.8ºC
[ Exact Mass ]:
183.01700
[ PSA ]:
96.26000
[ LogP ]:
1.80880
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LT8566000
- CHEMICAL NAME :
- 2-Furanacrylic acid, 5-nitro-
- CAS REGISTRY NUMBER :
- 6281-23-8
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C7-H5-N-O5
- MOLECULAR WEIGHT :
- 183.13
- WISWESSER LINE NOTATION :
- T5OJ BNW E1U1VQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 5 mg/L
- REFERENCE :
- TGANAK Tsitologiya i Genetika. Cytology and Genetics. For English translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 20,377,1986
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
36-43
[ Safety Phrases ]:
26-36/37
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
LT8566000
[ HS Code ]:
2932190090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2932190090
[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
Articles
Mutat. Res. 281(1) , 63-6, (1992)
Inducible stable DNA replication (iSDR) provoked by a damaging treatment with MMS, MNU, MNNG, NFAA, NFN, 4NQO, NAL or MMC, was followed in both repair-competent E. coli PQ35 and its uvrA derivative E....
DNA damage by 5-nitro-2-furylacrylic acid, a nitrofuran derivative.Chem. Biol. Interact. 63(2) , 185-94, (1987)
5-Nitro-2-furylacrylic acid (5-NFA) caused dose dependent inhibition of growth of Escherichia coli K-12 strain AB 2480 (uvr-, rec-), the 37% (D37) and 10% (D10) survival doses being 1.0 microgram/ml.h...
Mutagenic effects of two nitrofuran food preservatives.Neoplasma 29(6) , 675-84, (1982)
Two structurally related food additives, 3-(5-nitro-2-furyl)acrylic acid (5-NFAA) and 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide (AF-2) showed a marked mutagenic effect on Salmonella typhimurium strain...