GLUTACONIC ACID

[ Melting Point ]:
137-139ºC(lit.)

[ Molecular Formula ]:
C₅H₆O₄

[ Molecular Weight ]:
130.09900

[ Exact Mass ]:
130.02700

[ PSA ]:
74.60000

[ LogP ]:
0.10190

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

Click to get detail synthetic route

Precursor

DownStream

Effects of structural analogues of the substrate and allosteric regulator of the human mitochondrial NAD(P)+-dependent malic enzyme.

Bioorg. Med. Chem. 17 , 5414-9, (2009)

Fumarate, a four-carbon trans dicarboxylic acid, is the allosteric activator of the human mitochondrial NAD(P)(+)-dependent malic enzyme (m-NAD(P)-ME). In this paper, we discuss the effects of the str...

Induction of the mitochondrial permeability transition in vitro by short-chain carboxylic acids.

Biochem. Biophys. Res. Commun. 272(2) , 431-5, (2000)

We recently reported that acrylic acid (AA) induces the MPT in vitro, which we suggested might be a critical event in the acute inflammatory and hyperplastic response of the olfactory epithelium. The ...

Efficient synthesis and neuroprotective effect of substituted 1,3-diphenyl-2-propen-1-ones.

J. Med. Chem. 51 , 4054-8, (2008)

An efficient synthesis involving a key aldol reaction and biological properties of 1,3-diphenyl-2-propen-1-ones 8- 20 is described. The in vitro activity for 2,2-diphenyl-1-picrylhydrazyl (DPPH) radic...

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