PIP-199

Names

[ Name ]:
PIP-199

[Synonym ]:
MFCD04443596

Biological Activity

[Description]:

PIP-199 is a selective inhibitor of RMI (RecQ-mediated genome instability protein) core complex/MM2 interaction, with an IC50 of 36 μM. MM2 is the binding site of RMI complex on Fanconi anemia complementation group M protein (FANCM). PIP-199 can be used for the research of sensitizing resistant tumors to DNA crosslinking chemotherapeutics.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₂₈N₄O₃

[ Molecular Weight ]:
456.54

[ Storage condition ]:
-20°C

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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