3-(Diethylamino)-1-propanol

Names

[ CAS No. ]:
622-93-5

[ Name ]:
3-(Diethylamino)-1-propanol

[Synonym ]:
MFCD00002947
1-Propanol, 3-(diethylamino)-
3-(Diethylamino)propan-1-ol
3-(Diethylamino)-1-propanol
EINECS 210-759-1
1-Propanol, 3- (diethylamino)-

Biological Activity

[Description]:

3-Diethylamino-1-propanol is an tertiary amine compound with anticonvulsant activity[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. L M Leadbetter, et al. Neuromodulatory role of serotonin in the anticonvulsant activity of 2-phenylbenzoate of 3-diethylamino-1-propanol.HCl (JAW-669). Physiol Behav. 1989 Jul;46(1):35-7.

[2]. Ida M.Bernhardsen, et al. Vapour-liquid equilibrium study of tertiary amines, single and in blend with 3-(methylamino)propylamine, for post-combustion CO2 capture.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
189.5±0.0 °C at 760 mmHg

[ Melting Point ]:
-12.63°C (estimate)

[ Molecular Formula ]:
C₇H₁₇NO

[ Molecular Weight ]:
131.216

[ Flash Point ]:
65.6±0.0 °C

[ Exact Mass ]:
131.131012

[ PSA ]:
23.47000

[ LogP ]:
0.57

[ Appearance of Characters ]:
Liquid | Clear colorless to yellow

[ Vapour Pressure ]:
0.2±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.447

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UB1480000

CHEMICAL NAME :: 1-Propanol, 3-(diethylamino)-

CAS REGISTRY NUMBER :: 622-93-5

BEILSTEIN REFERENCE NO. :: 1734168

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H17-N-O

MOLECULAR WEIGHT :: 131.25

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 231 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 14,201,1959

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S16-S26-S7

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UB1480000

[ HS Code ]:
2922199090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Mechanistic study of the stereoselective polymerization of D,L-lactide using indium(III) halides.

J. Am. Chem. Soc. 132(33) , 11649-57, (2010)

We report the results of a comprehensive investigation of the recently discovered stereoselective and controlled polymerization of racemic lactide (D,L-LA) using an initiator prepared in situ from ind...

Related Compounds

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