Cyclohexyl acetate
Names
[ CAS No. ]:
622-45-7
[ Name ]:
Cyclohexyl acetate
[Synonym ]:
cyclohexanol acetate
Hexalin acetate
EINECS 210-736-6
Cyclohexane acetate
Cyclohexanyl acetate
Cyclohexanolazetat
MFCD00003850
acetic acid cyclohexyl ester
Adronal acetate
acetic acid cyclohexanyl ester
Chemical & Physical Properties
[ Density]:
0.966 g/mL at 25 °C(lit.)
[ Boiling Point ]:
172-173 °C(lit.)
[ Melting Point ]:
-77 °C
[ Molecular Formula ]:
C8H14O2
[ Molecular Weight ]:
142.19600
[ Flash Point ]:
136 °F
[ Exact Mass ]:
142.09900
[ PSA ]:
26.30000
[ LogP ]:
1.88220
[ Index of Refraction ]:
n20/D 1.439(lit.)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AG5075000
- CHEMICAL NAME :
- Acetic acid, cyclohexyl ester
- CAS REGISTRY NUMBER :
- 622-45-7
- BEILSTEIN REFERENCE NO. :
- 1906543
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C8-H14-O2
- MOLECULAR WEIGHT :
- 142.22
- WISWESSER LINE NOTATION :
- L6TJ AOV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,751,1979
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,359,1986
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,359,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 3000 mg/m3/45M
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - conjunctive irritation Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AHYGAJ Archiv fuer Hygiene. (Munich, Fed. Rep. Ger.) V.1-100, 1883-1928. For publisher information, see ZHPMAT. Volume(issue)/page/year: 78,260,1913
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6730 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 28,313,1974
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AHYGAJ Archiv fuer Hygiene. (Munich, Fed. Rep. Ger.) V.1-100, 1883-1928. For publisher information, see ZHPMAT. Volume(issue)/page/year: 78,260,1913
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 10 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 28,313,1974 *** REVIEWS *** TOXICOLOGY REVIEW AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 21,28,1960
Safety Information
[ Symbol ]:
GHS02, GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H226-H315
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R38
[ Safety Phrases ]:
S26-S28-S36/37/39
[ RIDADR ]:
UN 2243 3/PG 3
[ WGK Germany ]:
1
[ RTECS ]:
AG5075000
[ Packaging Group ]:
III
[ Hazard Class ]:
3.2
[ HS Code ]:
2915390090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2915390090
[ Summary ]:
2915390090. esters of acetic acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:5.5%. General tariff:30.0%
Articles
Food Chem. Toxicol. 46 Suppl 12 , S52-5, (2008)
A toxicologic and dermatologic review of cyclohexyl acetate when used as a fragrance ingredient is presented.