Methyl 5-hydroxynaphtho[1,2-b]furan-4-carboxylate

Names

[ Name ]:
Methyl 5-hydroxynaphtho[1,2-b]furan-4-carboxylate

[Synonym ]:
Methyl 5-hydroxynaphtho[1,2-b]furan-4-carboxylate
Naphtho[1,2-b]furan-4-carboxylic acid, 5-hydroxy-, methyl ester

Biological Activity

[Description]:

Furomollugin is a natural product with antioxidant and antibacterial activities, can be isolated from Rubia cordifolia. Furomollugin lacks potent anti-tyrosinase activity, but also exhibits significant anticancer property[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Xia L, et al. Anti-tyrosinase, antioxidant, and antibacterial activities of novel 5-hydroxy-4-acetyl-2,3-dihydronaphtho[1,2-b]furans. Eur J Med Chem. 2014 Oct 30;86:605-12.

[2]. Xia L, et al. Antioxidant and antibacterial evaluation of synthetic furomollugin and its diverse analogs[J]. Medicinal Chemistry Research, 2014, 23(7): 3528-3538.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
391.6±22.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₄H₁₀O₄

[ Molecular Weight ]:
242.227

[ Flash Point ]:
190.6±22.3 °C

[ Exact Mass ]:
242.057907

[ PSA ]:
59.67000

[ LogP ]:
3.92

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.694

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.