N-Nitrosomorpholine-d4

Names

[ CAS No. ]:
61578-30-1

[ Name ]:
N-Nitrosomorpholine-d4

[Synonym ]:
Nitrosomorpholine-d4
3,3,5,5-Tetradeutero-N-nitrosomorpholine
4-Nitrosomorpholine-d4
N-Nitrosomorpholine-d4

Biological Activity

[Description]:

N-Nitrosomorpholine-d4 is the deuterium labeled N-Nitrosomorpholine[1]. N-Nitrosomorpholine is a nitrosamine that is sensitive to light. N-nitrosomorpholine is a strong animal carcinogen[2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. K D Brunnemann, et al. N-Nitrosomorpholine and Other Volatile N-nitrosamines in Snuff Tobacco. Carcinogenesis. 1982;3(6):693-6.  

Chemical & Physical Properties

[ Density]:
1.37g/cm3

[ Boiling Point ]:
226.1ºC at 760 mmHg

[ Molecular Formula ]:
C4H4D4N2O2

[ Molecular Weight ]:
120.14300

[ Flash Point ]:
90.5ºC

[ Exact Mass ]:
120.08400

[ PSA ]:
41.90000

[ Index of Refraction ]:
1.546

Related Compounds