Oxytetracycline Dihydrate

Names

[ Name ]:
Oxytetracycline Dihydrate

[Synonym ]:
DOXYCYCLINE USP 23
MFCD00151234
trramycin
Oxy-tetracyclin
OXYTETRACYCLINEFEED
OXYCYCLINE
OXYTETRACYCLINE HCL BP
DOXYCYCLINE HYCHLATE
EINECS 209-271-1

Biological Activity

[Description]:

Oxytetracycline dihydrate is a broad-spectrum antibiotic that acts by inhibiting protein synthesis in bacteria[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Oxytetracycline dihydrate is a well studied polyketide natural product and is an important example of type II polyketide biosynthesis[1].

[References]

[1]. Pickens LB, et al. Oxytetracycline biosynthesis. J Biol Chem. 2010 Sep 3;285(36):27509-15.

Chemical & Physical Properties

[ Boiling Point ]:
845.6ºC at 760 mmHg

[ Melting Point ]:
181-182 °C

[ Molecular Formula ]:
C₂₂H₂₈N₂O₁₁

[ Molecular Weight ]:
496.46500

[ Flash Point ]:
465.2ºC

[ Exact Mass ]:
496.16900

[ PSA ]:
220.31000

[ Storage condition ]:
2~8°C

[ Water Solubility ]:
slightly soluble

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R36;R63

[ Safety Phrases ]:
S22-S24/25-S36/37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29413000

Customs

[ HS Code ]: 29413000

Articles

Experimental study of the impact of antimicrobial treatments on Campylobacter, Enterococcus and PCR-capillary electrophoresis single-strand conformation polymorphism profiles of the gut microbiota of chickens.

J. Med. Microbiol. 63(Pt 11) , 1552-60, (2014)

An experiment was conducted to compare the impact of antimicrobial treatments on the susceptibility of Campylobacter, Enterococcus faecium and Enterococcus faecalis, and on the diversity of broiler mi...

Development and validation of a liquid chromatographic/ tandem mass spectrometric method for determination of chlortetracycline, oxytetracycline, tetracycline, and doxycycline in animal feeds.

J. AOAC Int. 95(4) , 1010-5, (2012)

A selective and accurate LC/MS/MS method for the simultaneous determination of chlortetracycline (CTC), oxytetracycline (OTC), tetracycline (TC), and doxycycline (DC) in animal feeds was developed. Sa...

Heterologous expression and manipulation of three tetracycline biosynthetic pathways.

Angew. Chem. Int. Ed. Engl. 51(44) , 11136-40, (2012)

A very accommodating host: Three tetracycline biosynthetic pathways were overexpressed and manipulated in the heterologous host Streptomyces lividans K4-114. Through the inactivation of various genes ...

Related Compounds

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