1MVR
Names
[ CAS No. ]:
613-93-4
[ Name ]:
1MVR
[Synonym ]:
N-MethylbenzaMide 10GR
n-methylbenzenecarboxamide
N-Methylbenzamide
N-Methylbenzenamide
n-methyl-benzamid
N-methyl benzamide
EINECS 210-362-3
Benzamide,N-methyl-(6CI,7CI,8CI,9CI)
MFCD00011642
Benzamide, N-methyl-
1MVR
Biological Activity
[Description]:
[Related Catalog]:
[Target]
PDE10A
[In Vivo]
[References]
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
254.9±23.0 °C at 760 mmHg
[ Melting Point ]:
76-78 °C(lit.)
[ Molecular Formula ]:
C8H9NO
[ Molecular Weight ]:
135.163
[ Flash Point ]:
145.6±11.9 °C
[ Exact Mass ]:
135.068420
[ PSA ]:
29.10000
[ LogP ]:
1.66
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.519
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CV5570000
- CHEMICAL NAME :
- Benzamide, N-methyl-
- CAS REGISTRY NUMBER :
- 613-93-4
- BEILSTEIN REFERENCE NO. :
- 1209880
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C8-H9-N-O
- MOLECULAR WEIGHT :
- 135.18
- WISWESSER LINE NOTATION :
- 1MVR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 840 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 19,20,1971
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R20/21/22
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
CV5570000
Articles
Biochemistry 40(46) , 13980-9, (2001)
Peroxidases typically bind their reducing substrates weakly, with K(d) values in the millimolar range. The binding of benzhydroxamic acid (BHA) to ferric horseradish peroxidase isoenzyme C (HRPC) [K(d...
N-Methylanilide and N-methylbenzamide derivatives as phosphodiesterase 10A (PDE10A) inhibitors.Bioorg. Med. Chem. 21(19) , 6053-62, (2013)
PDE10A is a recently identified phosphodiesterase with a quite remarkable localization since the protein is abundant only in brain tissue. Based on this unique localization, research has focused exten...
Molecular electrostatic potential of orthopramides: implications for their interaction with the D-2 dopamine receptor.J. Med. Chem. 29(5) , 600-6, (1986)
The electronic properties of orthopramides, a group of selective D-2 dopamine receptor antagonists, were investigated by calculating molecular electrostatic potentials (MEP) of model compounds with th...