4-Methoxybiphenyl
Names
[ CAS No. ]:
613-37-6
[ Name ]:
4-Methoxybiphenyl
[Synonym ]:
EINECS 210-339-8
MFCD00014897
1-methoxy-4-phenylbenzene
Chemical & Physical Properties
[ Boiling Point ]:
157 °C (10 mmHg)
[ Melting Point ]:
86-90 °C(lit.)
[ Molecular Formula ]:
C13H12O
[ Molecular Weight ]:
184.23400
[ Flash Point ]:
157°C/10mm
[ Exact Mass ]:
184.08900
[ PSA ]:
9.23000
[ LogP ]:
3.36220
[ Index of Refraction ]:
1.556
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BZ8850000
- CHEMICAL NAME :
- Anisole, p-phenyl-
- CAS REGISTRY NUMBER :
- 613-37-6
- BEILSTEIN REFERENCE NO. :
- 2043157
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C13-H12-O
- MOLECULAR WEIGHT :
- 184.25
- WISWESSER LINE NOTATION :
- 1OR DR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5477 mg/kg/52W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Blood - lymphoma, including Hodgkin's disease
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,270,1962
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
BZ8850000
[ HS Code ]:
2909309090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2909309090
[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
Biochem. Pharmacol. 30(14) , 1915-9, (1981)
Influence of the sulphation inhibitor, 2,6-dichloro-4-nitrophenol, on the production and conjugation, of 4-hydroxybiphenyl generated from 4-methoxybiphenyl by rat isolated hepatocytes.
Biochem. Pharmacol. 36(18) , 3090-2, (1987)
Influence of cytochrome P-450 type on the pattern of conjugation of 4-hydroxybiphenyl generated from biphenyl or 4-methoxybiphenyl.
Xenobiotica 15(6) , 493-502, (1985)
The rate of production of 4-hydroxybiphenyl from 4-methoxybiphenyl in hepatocytes isolated from untreated rats was essentially identical to that from biphenyl in hepatocytes isolated from rats pretrea...