Chloroquinoline
Names
[ CAS No. ]:
612-62-4
[ Name ]:
Chloroquinoline
[Synonym ]:
2-Chloroquinoline 1GR
2CQ
Chloroquinoline
2-Chlor-chinolin
2-chloro-quinoline
Quinoline, 2-chloro-
EINECS 210-317-8
quinolyl chloride
Quinoline2-chloro
2-chloro-quinolin
2-Chloroquinoline
MFCD00006741
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
267.3±13.0 °C at 760 mmHg
[ Melting Point ]:
34-37 °C(lit.)
[ Molecular Formula ]:
C9H6ClN
[ Molecular Weight ]:
163.604
[ Flash Point ]:
141.2±5.4 °C
[ Exact Mass ]:
163.018875
[ PSA ]:
12.89000
[ LogP ]:
2.71
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.652
[ Water Solubility ]:
Insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VB2320000
- CHEMICAL NAME :
- Quinoline, 2-chloro-
- CAS REGISTRY NUMBER :
- 612-62-4
- BEILSTEIN REFERENCE NO. :
- 0112561
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H6-Cl-N
- MOLECULAR WEIGHT :
- 163.61
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
VB2320000
[ HS Code ]:
2933499090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933499090
[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Eur. J. Med. Chem. 46 , 1897-905, (2011)
A new series of chloroquinoline based chalcones were synthesized and evaluated for in vitro antiamoebic and antimalarial activities. The results showed that out of fifteen compounds, four were found t...
Ruthenium-catalyzed cyclization of anilides with substituted propiolates or acrylates: an efficient route to 2-quinolinones.Org. Lett. 16(13) , 3568-71, (2014)
A Ru-catalyzed cyclization of anilides with propiolates or acrylates affording 2-quinolinones having diverse functional groups in good to excellent yields is described. Later, 2-quinolinones were conv...
Chemoenzymatic synthesis of chiral 2,2'-bipyridine ligands and their N-oxide derivatives: applications in the asymmetric aminolysis of epoxides and asymmetric allylation of aldehydes.Org. Biomol. Chem. 8(5) , 1081-90, (2010)
A series of enantiopure 2,2'-bipyridines have been synthesised from the corresponding cis-dihydrodiol metabolites of 2-chloroquinolines. Several of the resulting hydroxylated 2,2'-bipyridines were fou...