2-Nitrobenzyl chloride

Names

[ CAS No. ]:
612-23-7

[ Name ]:
2-Nitrobenzyl chloride

[Synonym ]:
Toluene, α-chloro-o-nitro-
EINECS 210-300-5
2-Nitrobenzyl chloride
Benzene, 1- (chloromethyl)-2-nitro-
1-(Chloromethyl)-2-nitrobenzene
Benzene, 1-(chloromethyl)-2-nitro-
MFCD00007185

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
269.0±0.0 °C at 760 mmHg

[ Melting Point ]:
46-48 °C(lit.)

[ Molecular Formula ]:
C₇H₆ClNO₂

[ Molecular Weight ]:
171.581

[ Flash Point ]:
112.7±20.4 °C

[ Exact Mass ]:
171.008713

[ PSA ]:
45.82000

[ LogP ]:
2.22

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.574

[ Stability ]:
Stable. Incompatible with bases, moisture, acohols, oxidizing agents, amines. Corrodes steel.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XS9092000

CHEMICAL NAME :: Toluene, alpha-chloro-o-nitro-

CAS REGISTRY NUMBER :: 612-23-7

BEILSTEIN REFERENCE NO. :: 0388396

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C7-H6-Cl-N-O2

MOLECULAR WEIGHT :: 171.59

WISWESSER LINE NOTATION :: WNR B1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA repair

TEST SYSTEM :: Bacteria - Bacillus subtilis

DOSE/DURATION :: 50 ug/disc

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 170,11,1986

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
XS9092000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2904909090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Nitrobenzyl mustard quaternary salts: a new class of hypoxia-selective cytotoxins capable of releasing diffusible cytotoxins on bioreduction.

Int. J. Radiat. Oncol. Biol. Phys. 29(2) , 317-21, (1994)

To explore the utility of a new class of compounds, nitrobenzyl mustard quaternary salts, as hypoxia-selective prodrugs of diffusible cytotoxins.The parent compound N,N-bis(2-chloroethyl)-N-methyl-N-(...

A cell-free protein synthesis system as an investigational tool for the translation stop processes.

FEBS Lett. 517(1-3) , 211-4, (2002)

Using Escherichia coli cell-free protein synthesis system and aminoacylated amber suppressor tRNA, we successfully inserted an unnatural amino acid S-(2-nitrobenzyl)cysteine into human erythropoietin....

Influence of steric effects on the excited triplet-state lifetime of 2, 2'-dinitrostilbene and 2, 2', 4, 4', 6, 6'-hexanitrostilbene in acetonitrile solution. Smit KJ.

J. Phys. Chem. 96(16) , 6555-6558, (1992)