2-Methoxycinnamic acid

Names

[ Name ]:
2-Methoxycinnamic acid

[Synonym ]:
O-METHOXYCINNAMIC ACID
2-Methoxycinnamic acid
2-Methoxyciamic acid
EINECS 228-047-4
2-MeOC6H4CH=CHCOOH
RARECHEM BK HC T255
Cinnamic acid,o-methoxy
2-methoxy cinnamic acid
trans-ortho-methoxy-cinnamic acid
(2E)-3-(2-Methoxyphenyl)acrylic acid
o-methoxy cinnamic acid
2-Propenoic acid, 3-(2-methoxyphenyl)-, (2E)-
MFCD00064238
METHOXYCINNAMIC ACID,2
TRANS-2-METHOXYCINNAMIC ACID

Biological Activity

[Description]:

2-Methoxycinnamic acid is a noncompetitive inhibitor of tyrosinase[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Lee HS, et al. Tyrosinase inhibitors of Pulsatilla cernua root-derived materials. J Agric Food Chem. 2002 Mar 13;50(6):1400-3.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
325.1±17.0 °C at 760 mmHg

[ Melting Point ]:
182-186 °C

[ Molecular Formula ]:
C₁₀H₁₀O₃

[ Molecular Weight ]:
178.185

[ Flash Point ]:
130.3±14.4 °C

[ Exact Mass ]:
178.062988

[ PSA ]:
46.53000

[ LogP ]:
2.42

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.591

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Cinnamic acid and its derivatives inhibit fructose-mediated protein glycation.

Int. J. Mol. Sci. 13 , 1778-89, (2012)

Cinnamic acid and its derivatives have shown a variety of pharmacologic properties. However, little is known about the antiglycation properties of cinnamic acid and its derivatives. The present study ...