2-Hydroxy acid

Names

[ CAS No. ]:
609-71-2

[ Name ]:
2-Hydroxy acid

[Synonym ]:
2-hydroxy-3-nicotinic acid
3-Carboxy-2-pyridone
3-pyridinecarboxylic acid, 1,2-dihydro-2-oxo-
2-hydroxy-3-carboxypyridine
2-hydroxynicotininic acid
T6MVJ CVQ
2-Hydroxy-3-picolinic acid
2-Hydroxynicotinic a
MFCD00010100
2-hydroxyl nicotinic acid
3-Pyridinecarboxylic acid, 2-hydroxy-
2-Hydroxypyridine-3-carboxylic acid
1,2-Dihydro-2-oxo-3-pyridinecarboxylic acid
EINECS 210-198-2
2-oxy-pyridine-3-carboxylic acid
2-Oxo-1,2-dihydropyridine-3-carboxylic acid
2-Hydroxynicotinicacid
2-Oxo-1,2-dihydro-3-pyridinecarboxylic acid
2-Hydroxy acid

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
427.5±30.0 °C at 760 mmHg

[ Melting Point ]:
258-261 °C(lit.)

[ Molecular Formula ]:
C₆H₅NO₃

[ Molecular Weight ]:
139.109

[ Flash Point ]:
212.4±24.6 °C

[ Exact Mass ]:
139.026947

[ PSA ]:
70.42000

[ LogP ]:
-0.32

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.626

[ Water Solubility ]:
0.1 M NaOH: 0.1 g/mL, clear

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

New possible chelating agents of clinical interest for iron(III): 2-hydroxynicotinic acid and 3-hydroxypicolinic acid. A thermodynamic study.

Ann. Chim. 91(9-10) , 595-603, (2001)

The formation of complexes between iron(III) and two ligands of possible relevance to chelation therapy, 2-hydroxynicotinic acid and 3-hydroxypicolinic acid, in aqueous 0.6 m (Na)Cl at 25 degrees C, h...

Permeation of aromatic carboxylic acids across lipid bilayers: the pH-partition hypothesis revisited.

Biophys. J. 89(3) , 1802-11, (2005)

According to the pH-partition hypothesis the charged species of organic compounds do not contribute to lipid bilayer permeation as they generally show negligible partitioning into n-octanol. With this...

Comparing the lipid membrane affinity and permeation of drug-like acids: the intriguing effects of cholesterol and charged lipids.

Pharm. Res. 24(8) , 1457-72, (2007)

Lipid bilayers regulate the passage of solutes into and between cellular compartments. A general prerequisite for this passage is the partitioning of the solute into the bilayer. We investigated the r...