(2S)-3-Chlorpropan-1,2-diol
Names
[ CAS No. ]:
60827-45-4
[ Name ]:
(2S)-3-Chlorpropan-1,2-diol
[Synonym ]:
(S)-3-Chloro-1,2-propanediol
1,2-Propanediol, 3-chloro-, (S)-
EINECS 202-492-4
Q1YQ1G &&S Form
(2S)-3-chloropropane-1,2-diol
(2S)-3-Chloro-1,2-propanediol
1,2-Propanediol, 3-chloro-, (2S)-
MFCD00210270
(2S)-3-Chlorpropan-1,2-diol
(S)-(+)-3-chloro-1,2-propanediol
S-2-Chloro-1,2-propanediol
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
213.0±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C3H7ClO2
[ Molecular Weight ]:
110.539
[ Flash Point ]:
113.3±21.8 °C
[ Exact Mass ]:
110.013458
[ PSA ]:
40.46000
[ LogP ]:
-0.76
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.474
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TY4202300
- CHEMICAL NAME :
- 1,2-Propanediol, 3-chloro-, (S)-
- CAS REGISTRY NUMBER :
- 60827-45-4
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C3-H7-O2
- MOLECULAR WEIGHT :
- 75.10
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 45500 ug/kg
- SEX/DURATION :
- male 14 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 51,105,1977
Safety Information
[ Symbol ]:
GHS05, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H312-H318
[ Precautionary Statements ]:
P280-P301 + P310-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R21;R23/25;R36/37/38;R62;R68
[ Safety Phrases ]:
S26-S28-S39-S45-S36/37/39
[ RIDADR ]:
UN 2689 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
TY4202300
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2905590090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2905590090
[ Summary ]:
2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
J. Biosci. Bioeng. 113(1) , 79-83, (2012)
Tris(1,3-dichloro-2-propyl) phosphate (TDCPP), a flame retardant, is regarded as a potentially toxic and persistent environmental contaminant. We previously isolated a TDCPP-degrading bacterium, Sphin...
Passage of MHPG from plasma to CSF in a non-human primate.Rev. Med. Chir. Soc. Med. Nat. Iasi. 115(4) , 1278-82, (2011)
In experimental protocols with humans and non-human primates, cerebrospinal fluid (CSF) concentrations of 3-methoxy-4-hydroxyphenylethylene glycol (MHPG), the predominant end-product of norepinephrine...
Fatty acid esters of monochloropropanediol (MCPD) and glycidol in refined edible oils.Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 30(1) , 46-51, (2013)
Recently, fatty acid esters of monochloropropanediol (MCPD) and that of glycidol have been reported in refined edible oils. Since then a wealth of research has been published on the factors influencin...