equilin benzoate

Names

[ CAS No. ]:
6030-80-4

[ Name ]:
equilin benzoate

[Synonym ]:
MFCD00468046

Chemical & Physical Properties

[ Density]:
1.24g/cm3

[ Boiling Point ]:
541ºC at 760 mmHg

[ Melting Point ]:
193-196ºC(lit.)

[ Molecular Formula ]:
C₂₅H₂₄O₃

[ Molecular Weight ]:
372.45600

[ Flash Point ]:
235.6ºC

[ Exact Mass ]:
372.17300

[ PSA ]:
43.37000

[ LogP ]:
5.25110

[ Index of Refraction ]:
1.634

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KD7875000

CHEMICAL NAME :: Equilin, benzoate

CAS REGISTRY NUMBER :: 6030-80-4

BEILSTEIN REFERENCE NO. :: 3172244

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C25-H24-O3

MOLECULAR WEIGHT :: 372.49

WISWESSER LINE NOTATION :: L E5 B666 FV JUTTT&J E1 DOVR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 96 mg/kg/48W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Blood - lymphoma, including Hodgkin's disease Skin and Appendages - tumors

REFERENCE :: ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 56,482,1949

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 42 mg/kg/21W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

REFERENCE :: CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 122,183,1936

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 148 mg/kg/37W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Reproductive - Tumorigenic effects - uterine tumors

REFERENCE :: YJBMAU Yale Journal of Biology and Medicine. (333 Cedar St., New Haven, CT 06510) V.1- 1928- Volume(issue)/page/year: 12,213,1939

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
40

[ Safety Phrases ]:
S36

[ WGK Germany ]:
3

[ RTECS ]:
KD7875000