Enterocin

Names

[ Name ]:
Enterocin

[Synonym ]:
Enterocin,vulgamycin
3,6-Methanocyclopenta(C)pyran-1(3H)-one,7-benzoylhexahydro-4A,6,7A,8-tetrahydroxy-5-(4-methoxy-2-oxo-2H-pyran-6-yl)-,(3R,4ar,5S,6S,7S,7as,8R)
Vulgamycin

Biological Activity

[Description]:

Enterocin, an antibiotic, has static activities against gram-positive and gram-negative bacteria and no activity against fungi and yeast[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. N Miyairi, et al, Enterocin, a new antibiotic taxonomy, isolation and characterization. J Antibiot (Tokyo). 1976 Mar;29(3):227-35.

Chemical & Physical Properties

[ Density]:
1.67 g/cm3

[ Boiling Point ]:
726.3ºC at 760 mmHg

[ Molecular Formula ]:
C₂₂H₂₀O₁₀

[ Molecular Weight ]:
444.38800

[ Flash Point ]:
257.4ºC

[ Exact Mass ]:
444.10600

[ PSA ]:
163.73000

[ Index of Refraction ]:
1.712

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: PB9245500

CHEMICAL NAME :: 3,6-Methanocylopenta(c)pyran-1(3H)-one, hexahydro-7-benzoyl-5-(4-methoxy-2-oxo-2H-pyran-6- yl)-4a,6,7a,8-tetrahydroxy-, (3R-(3-alpha,4a-beta,5-alpha,6-beta,7-beta,7a-beta,8R *))-

CAS REGISTRY NUMBER :: 59678-46-5

LAST UPDATED :: 199212

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C22-H20-O10

MOLECULAR WEIGHT :: 444.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 29,227,1976

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 29,227,1976

Related Compounds

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