Trityl Bromide

Names

[ CAS No. ]:
596-43-0

[ Name ]:
Trityl Bromide

[Synonym ]:
α-Bromotriphenylmethane
Benzene, 1,1',1''-(bromomethylidyne)tris-
triphenyl methyl bromide
1,3,5-Triphenibenzene
bromotriphenyl-methan
1,1',1''-(Bromomethanetriyl)tribenzene
bromotriphenylmethane
Trityl Bromide
[Ph3C][B(C6F5)4]
TRIPHENYLBROMOMETHANE
Methane,bromotriphenyl
MFCD00000120
EINECS 209-884-4

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
381.2±0.0 °C at 760 mmHg

[ Melting Point ]:
152-154 °C(lit.)

[ Molecular Formula ]:
C₁₉H₁₅Br

[ Molecular Weight ]:
323.226

[ Flash Point ]:
183.0±12.3 °C

[ Exact Mass ]:
322.035706

[ LogP ]:
6.51

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.628

[ Storage condition ]:
0-6°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents. Combustible.

[ Water Solubility ]:
dioxane: 0.1 g/mL, clear

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: PA5550000

CHEMICAL NAME :: Methane, bromotriphenyl-

CAS REGISTRY NUMBER :: 596-43-0

BEILSTEIN REFERENCE NO. :: 1878494

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C19-H15-Br

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04015

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
PA5550000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2903999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5.

J. Med. Chem. 51 , 1115-25, (2008)

The human kinesin Eg5 is a potential drug target for cancer chemotherapy. Eg5 specific inhibitors cause cells to block in mitosis with a characteristic monoastral spindle phenotype. Prolonged metaphas...