Fluoxetine Hydrochloride

Names

[ Name ]:
Fluoxetine Hydrochloride

[Synonym ]:
N-Methyl-3-phenyl-3-[4-(trifluormethyl)phenoxy]propan-1-aminhydrochlorid
(±)-N-Methyl-3-phenyl-3-[(a,a,a-trifluoro-p-tolyl)oxy]propylamine Hydrochloride
MFCD00214288
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride
Sarafem
N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-1-propanamine hydrochloride (1:1)
Prozac
(±)-N-Methyl-g-[4-(trifluoromethyl)phenoxy]benzenepropanamine Hydrochloride
EINECS 260-101-2
N-méthyl-3-phényl-3-[4-(trifluorométhyl)phénoxy]propan-1-amine chlorhydrate
Fluoxetine HCl
Reneuron
UNII:I9W7N6B1KJ
Benzenepropanamine, N-methyl-γ-[4-(trifluoromethyl)phenoxy]-, hydrochloride (1:1)
fluoxetine hydrochloride
N-Methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine Hydrochloride
(±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride
N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride (1:1)

Chemical & Physical Properties

[ Density]:
1.254g/cm3

[ Boiling Point ]:
569.2ºC at 760 mmHg

[ Melting Point ]:
158.4-158.9ºC

[ Molecular Formula ]:
C₁₇H₁₉ClF₃NO

[ Molecular Weight ]:
345.787

[ Flash Point ]:
298ºC

[ Exact Mass ]:
345.110718

[ PSA ]:
21.26000

[ LogP ]:
5.62790

[ Index of Refraction ]:
1.63

[ Storage condition ]:
-20°C Freezer

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
H2O: 4 mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
22-38-41

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol, solution

[ WGK Germany ]:
3

[ RTECS ]:
UI4050000

[ HS Code ]:
2922199090

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

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Phytother Res. 28(4) , 579-85, (2014)

Curcumin, an active ingredient of Curcuma longa Linn (Zingiberaceae), has shown potential antidepressant-like activity in animal studies. The objectives of this trial were to compare the efficacy and ...

Anti-depressant like activity of N-n-butyl-3-methoxyquinoxaline-2-carboxamide (6o) a 5-HT3 receptor antagonist.

Indian J. Exp. Biol. 51(6) , 435-43, (2013)

The compound 6o (at 0.5, 1 and 2 mg/kg, ip) with optimum log P and pA2 value, was subjected to forced swim test (FST) and tail suspension test (TST). The compound 6o significantly reduced the duration...

K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac.

Science 347(6227) , 1256-9, (2015)

TREK-2 (KCNK10/K2P10), a two-pore domain potassium (K2P) channel, is gated by multiple stimuli such as stretch, fatty acids, and pH and by several drugs. However, the mechanisms that control channel g...