mSIRK

Names

[ CAS No. ]:
593267-11-9

[ Name ]:
mSIRK

Biological Activity

[Description]:

mSIRK (G-Protein βγ Binding Peptide) is an cell-permeable activator of ERK1/2, with EC50 of 2.5-5 μM. mSIRK disrupts the interaction between α and βγ subunits and promotes α subunit dissociation without stimulating nucleotide exchange[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> MAPK/ERK Pathway >> ERK
Signaling Pathways >> Stem Cell/Wnt >> ERK

[References]

[1]. Farida Goubaeva, et al. Stimulation of Cellular Signaling and G Protein Subunit Dissociation by G Protein βγ Subunit-binding Peptides. J Biol Chem. 2003 May 30;278(22):19634-41.  

Chemical & Physical Properties

[ Molecular Formula ]:
C93H150N20O25

[ Molecular Weight ]:
1948.31

Related Compounds

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