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5-METHYLCYTOSINE HYDROCHLORIDE

Names

[ CAS No. ]:
58366-64-6

[ Name ]:
5-METHYLCYTOSINE HYDROCHLORIDE

[Synonym ]:
2(1H)-pyrimidinone, 4-amino-5-methyl-, hydrochloride (1:1)
4-Amino-5-methylpyrimidin-2(1H)-one hydrochloride (1:1)
EINECS 261-223-9
2(1H)-pyrimidinone, 3,4-dihydro-4-imino-5-methyl-, hydrochloride (1:1)
6-Amino-5-methylpyrimidin-2(1H)-onhydrochlorid(1:1)
2(1H)-Pyrimidinone, 6-amino-5-methyl-, hydrochloride (1:1)
6-amino-5-methylpyrimidin-2(1H)-one hydrochloride (1:1)
4-Imino-5-methyl-3,4-dihydropyrimidin-2(1H)-one hydrochloride (1:1)
MFCD00035313
6-amino-5-methyl-1H-pyrimidin-2-one,hydrochloride
6-Amino-5-methyl-2(1H)-pyrimidinone hydrochloride (1:1)

Chemical & Physical Properties

[ Melting Point ]:
293-295°C effervescence

[ Molecular Formula ]:
C5H8ClN3O

[ Molecular Weight ]:
161.589

[ Exact Mass ]:
161.035583

[ PSA ]:
72.03000

[ LogP ]:
1.45600

[ Storage condition ]:
Store at RT.

[ Stability ]:
This compound looses chloride readily. Keep container tightly closed, and store in freezer.

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Electrospray ionization mass spectrometry of non-covalent complexes formed between N-alkylimidazolium-containing zwitterionic sulfonates and protonated bases.

Eur. J. Mass Spectrom. (Chichester, Eng.) 20(6) , 467-75, (2015)

This paper describes non-covalent complexes between zwitterionic 3-(1-alkyl-3N-imidazolio)- propane-1-sulfonates and different amines. Electrospray ionization (ESI) mass spectrometry and collision- in...

Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation.

Cell 155(7) , 1545-55, (2013)

TET proteins oxidize 5-methylcytosine (5mC) on DNA and play important roles in various biological processes. Mutations of TET2 are frequently observed in myeloid malignance. Here, we present the cryst...

3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models.

BMC Pharmacol. Toxicol. 14 , 11, (2013)

The spatial organization of the genome is being evaluated as a novel indicator of toxicity in conjunction with drug-induced global DNA hypomethylation and concurrent chromatin reorganization. 3D quant...


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