Norcepharadione B

Names

[ Name ]:
Norcepharadione B

[Synonym ]:
1,2-Dimethoxy-4H-dibenzo[de,g]quinoline-4,5(6H)-dione
norcepharadione
4H-Dibenzo[de,g]quinoline-4,5(6H)-dione, 1,2-dimethoxy-

Biological Activity

[Description]:

Norcepharadione B is an alkaloid that can be isolated from Houttuynia cordata. Norcepharadione B exhibits moderate cytotoxicity against A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15 cell line with ED50s of 40, 26.4, 40, 14.2 and 38.2 μg/mL, respectively[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Kim, S.-K., et al. Cytotoxic alkaloids fromHouttuynia cordate. Archives of Pharmacal Research, 24(6), 518–521.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₁₈H₁₃NO₄

[ Molecular Weight ]:
307.30

[ Exact Mass ]:
307.084473

[ PSA ]:
68.39000

[ LogP ]:
2.39

[ Index of Refraction ]:
1.700

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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