Azuleno[4,5-b]furan-2 (3H)-one, 8-(.beta.-D-glucopyranosyloxy)decahydro-3,6,9-tris(methylene)-, [3aS-(3a.alpha.,6a.alpha.,8.beta.,9a.alpha.,9b.beta.)]-

Names

[ Name ]:
Azuleno[4,5-b]furan-2 (3H)-one, 8-(.beta.-D-glucopyranosyloxy)decahydro-3,6,9-tris(methylene)-, [3aS-(3a.alpha.,6a.alpha.,8.beta.,9a.alpha.,9b.beta.)]-

[Synonym ]:
glucozaluzanin
glucozaluzanin C

Biological Activity

[Description]:

Glucozaluzanin C is a lignan isolated from the MeOH extract of the roots of Ainsliaea acerifolia (Compositae). Glucozaluzanin C has ED50 value of 2.45 μg/mL, 1.37μg/mL, 0.40 μg/mL, 1.41 μg/mL, 1.43 μg/mL for A549 cells, SK-OV-3 cells, SK-MEL-2 cells, XF498 cells, HCT15 cells, respectively[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Choi SZ, et al. Cytotoxic terpenes and lignans from the roots of Ainsliaea acerifolia. Arch Pharm Res. 2006 Mar;29(3):203-8.

Chemical & Physical Properties

[ Density]:
1.38g/cm3

[ Boiling Point ]:
659.9ºC at 760 mmHg

[ Molecular Formula ]:
C₂₁H₂₈O₈

[ Molecular Weight ]:
408.44200

[ Flash Point ]:
232.1ºC

[ Exact Mass ]:
408.17800

[ PSA ]:
125.68000

[ Index of Refraction ]:
1.601

Synthetic Route

Click to get detail synthetic route

Related Compounds

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