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1,7-Naphthalenediol

Names

[ CAS No. ]:
575-38-2

[ Name ]:
1,7-Naphthalenediol

[Synonym ]:
1,7-dihydroxy-naphthalene
1,7-Naphthalenediol
1,7-dihydroxynaphthalenen
1,7-DihydroxylNaphthalene
1,7-Dihydroxynaphthalene
1,7-Dihydroxynaphtalen
1,7-Dihydroxynaphtha
naphthalene-1,7-diol
MFCD00035720
EINECS 209-383-0
7-hydroxy-1-naphthol
1,7-Dihydroxynaphthalin
1,7-Dihydroxy naphthylene
7-hydroxy-naphtalen-1-ol
1,7-Napthalenediol

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
375.4±15.0 °C at 760 mmHg

[ Melting Point ]:
180-184 °C(lit.)

[ Molecular Formula ]:
C10H8O2

[ Molecular Weight ]:
160.169

[ Flash Point ]:
193.5±15.0 °C

[ Exact Mass ]:
160.052429

[ PSA ]:
40.46000

[ LogP ]:
1.94

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.726

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QJ4746666
CHEMICAL NAME :
1,7-Naphthalenediol
CAS REGISTRY NUMBER :
575-38-2
LAST UPDATED :
199806
DATA ITEMS CITED :
1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
1600 nmol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 371,293,1996

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
QJ4746666

[ HS Code ]:
2907299090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2907299090

[ Summary ]:
2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

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J. Med. Chem. 49 , 1932-8, (2006)

The antiproliferative activity of the 14 isomeric monoxylosylated dihydroxynaphthalenes has been tested in vitro toward normal HFL-1 and 3T3 A31 cells as well as transformed T24 and 3T3 SV40 cells. Th...


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