Aureothricin

Names

[ CAS No. ]:
574-95-8

[ Name ]:
Aureothricin

[Synonym ]:
propionopyrrothine
Aureothricin
Anzeothricin
4-methyl-6-propionylamino-4H-[1,2]dithiolo[4,3-b]pyrrol-5-one
N-(4-methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)-propionamide
N-(4-Methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)-propionamid
Farcinicin
Propiopyvothine
Aurethricin

Biological Activity

[Description]:

Aureothricin is a dithiolopyrrolone (DTP) antibiotic first isolated from Streptomyces and exhibits relatively broad-spectrum antibiotic activity. Aureothricin can inhibit adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

Bacteral[1]

[References]

[1]. Li B, et al. Dithiolopyrrolones: biosynthesis, synthesis, and activity of a unique class of disulfide-containing antibiotics. Nat Prod Rep. 2014 Jul;31(7):905-23.

Chemical & Physical Properties

[ Density]:
1.48g/cm3

[ Boiling Point ]:
479.1ºC at 760 mmHg

[ Molecular Formula ]:
C₉H₁₀N₂O₂S₂

[ Molecular Weight ]:
242.31800

[ Flash Point ]:
243.6ºC

[ Exact Mass ]:
242.01800

[ PSA ]:
111.07000

[ LogP ]:
2.61110

[ Index of Refraction ]:
1.694

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.