Charantin

Names

[ Name ]:
Charantin

[Synonym ]:
Monordica Charantia

Biological Activity

[Description]:

Charantin is a steroidal saponin isolated from Momordica charantia, and has insulin-like activity, by increasing the release of insulin and slowing down gluconeogenesis. Charantin can against GSK-3[1].

[Related Catalog]:

Signaling Pathways >> Stem Cell/Wnt >> GSK-3

Research Areas >> Metabolic Disease

Signaling Pathways >> PI3K/Akt/mTOR >> GSK-3

[Target]

GSK-3[1]

[References]

[1]. Wang HY, et al. Differential anti-diabetic effects and mechanism of action of charantin-rich extract of Taiwanese Momordica charantia between type 1 and type 2 diabetic mice. Food Chem Toxicol. 2014 Jul;69:347-56.

Chemical & Physical Properties

[ Melting Point ]:
266-268℃

[ Molecular Formula ]:
C₁₀₅H₁₇₈O₁₈

[ Molecular Weight ]:
822.92