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AZD 2098

Names

[ CAS No. ]:
566203-88-1

[ Name ]:
AZD 2098

[Synonym ]:
2,3-Dichloro-N-(3-methoxy-2-pyrazinyl)benzenesulfonamide
Benzenesulfonamide, 2,3-dichloro-N-(3-methoxy-2-pyrazinyl)-

Biological Activity

[Description]:

AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor, used for asthma research.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> CCR
Signaling Pathways >> Immunology/Inflammation >> CCR
Research Areas >> Inflammation/Immunology

[Target]

CCR4


[References]

[1]. Asher Mullard. Cancer charity sees success re-prioritizing industry's shelved compounds. Nature Reviews Drug Discovery 13, 319–321 (2014)


[Related Small Molecules]

INCB3344 | Cenicriviroc | INCB8761(PF-4136309) | RS504393 | RS-102895 hydrochloride | BX 471 | TAK-779 | Vercirnon | MK-0812 Succinate | CCX140 | INCB 3284 | ZK 756326 | CCR2-RA-[R] | BMS-813160 | (D-Ala1)-Peptide T amide

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
489.3±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C11H9Cl2N3O3S

[ Molecular Weight ]:
334.178

[ Flash Point ]:
249.7±31.5 °C

[ Exact Mass ]:
332.974182

[ LogP ]:
3.32

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.628

[ Storage condition ]:
2-8℃

Related Compounds

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