cholest-5-en-3β,7α-diol

Names

[ CAS No. ]:
566-26-7

[ Name ]:
cholest-5-en-3β,7α-diol

[Synonym ]:
7|A-hydroxycholesterol
7Alpha-Hydroxy Cholesterol
Cholest-5-en-3beta,7alpha-diol
Cholest-5-ene-3beta,7alpha-diol
(3S,7S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
7alpha-hydroxycholesterol
7alpha-Cholesterol

Biological Activity

[Description]:

7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Ferderbar S, et al. Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus. Diabetes Metab Res Rev. 2007 Jan;23(1):35-42.

[2]. Kitano S, et al. Oxidative status of human low density lipoprotein isolated by anion-exchange high-performance liquid chromatography--assessment by total hydroxyoctadecadienoic acid, 7-hydroxycholesterol, and 8-iso-prostaglandin F(2alpha). Anal Chim Acta. 2007 Feb 28;585(1):86-93.

Chemical & Physical Properties

[ Density]:
1.03g/cm3

[ Boiling Point ]:
515.3ºC at 760mmHg

[ Melting Point ]:
168-170ºC

[ Molecular Formula ]:
C₂₇H₄₆O₂

[ Molecular Weight ]:
402.65300

[ Flash Point ]:
214.7ºC

[ Exact Mass ]:
402.35000

[ PSA ]:
40.46000

[ LogP ]:
6.35950

[ Index of Refraction ]:
1.536

[ Storage condition ]:
-20°C

Precursor & DownStream

Precursor

DownStream

Related Compounds

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