Benzenesulfonamide,3-amino-N-(5-chloro-2-pyrimidinyl)-
Names
[ CAS No. ]:
565-36-6
[ Name ]:
Benzenesulfonamide,3-amino-N-(5-chloro-2-pyrimidinyl)-
[Synonym ]:
Metachloridine
WR-6010
3-amino-N-5-chloropyrimidin-2-ylbenzenesulphonamide
Chemical & Physical Properties
[ Density]:
1.588g/cm3
[ Boiling Point ]:
554.9ºC at 760mmHg
[ Molecular Formula ]:
C10H9ClN4O2S
[ Molecular Weight ]:
284.72200
[ Flash Point ]:
289.4ºC
[ Exact Mass ]:
284.01300
[ PSA ]:
106.35000
[ LogP ]:
3.24800
[ Index of Refraction ]:
1.683
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OY2210000
- CHEMICAL NAME :
- Metanilamide, N'-(5-chloro-2-pyrimidyl)-
- CAS REGISTRY NUMBER :
- 565-36-6
- BEILSTEIN REFERENCE NO. :
- 0261399
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C10-H9-Cl-N4-O2-S
- MOLECULAR WEIGHT :
- 284.74
- WISWESSER LINE NOTATION :
- T6N CNJ BMSWR CZ& EG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CHTHBK Chemotherapy (Basel). (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.13- 1968- Volume(issue)/page/year: 13,289,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,469,1971
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,469,1971
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 1083 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CHTHBK Chemotherapy (Basel). (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.13- 1968- Volume(issue)/page/year: 13,289,1968