3-Nitrophenylsulfonyl chloride

Names

[ CAS No. ]:
121-51-7

[ Name ]:
3-Nitrophenylsulfonyl chloride

[Synonym ]:
3-O2N-PhSO2Cl
m-nitrobenzenesulphonyl chloride
Benzenesulfonyl chloride,m-nitro
3-nitro-benzenesulfonyl chloride
m-Nitrophenylsulfonyl chloride
3-Nitrobenzenesulfonyl chloride
Benzenesulfonyl chloride, 3-nitro-
meta-nitrobenzenesulfonyl chloride
M-NITROBENZENESULFONYL CHLORIDE
MFCD00007435
3-Nitrophenylsulfonyl chloride
Benzenesulfonyl chloride,3-nitro
3-nitrobenzene-1-sulfonyl chloride
Benzenesulfonyl chloride, m-nitro-
3-Nitrobenzenesulphonyl chloride
EINECS 204-476-2

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
341.0±25.0 °C at 760 mmHg

[ Melting Point ]:
61-62 °C(lit.)

[ Molecular Formula ]:
C₆H₄ClNO₄S

[ Molecular Weight ]:
221.618

[ Flash Point ]:
160.0±23.2 °C

[ Exact Mass ]:
220.954956

[ PSA ]:
88.34000

[ LogP ]:
2.21

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.588

[ Water Solubility ]:
Decomposes

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R14;R29;R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S8

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2904909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110alpha inhibitors.

Bioorg. Med. Chem. 15(1) , 403-12, (2007)

3-{1-[(4-Fluorophenyl)sulfonyl]-1H-pyrazol-3-yl}-2-methylimidazo[1,2-a]pyridine, 2a, was discovered in our chemical library as a novel p110alpha inhibitor with an IC(50) of 0.67microM, through screeni...

Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.

Bioorg. Med. Chem. Lett. 16 , 2842-2845, (2006)

High-throughput screening of a small-molecule compound library resulted in the identification of a novel series of N-acyl 2-aminobenzimidazoles that are potent inhibitors of interleukin-1 receptor-ass...