2-Hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione
Names
[ CAS No. ]:
5596-17-8
[ Name ]:
2-Hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione
[Synonym ]:
4,7-Epoxy-1H-isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-hydroxy-, (3aR,4S,7R,7aS)-
(1R,2S,6R,7S)-4-Hydroxy-10-oxa-4-azatricyclo[5.2.1.0]dec-8-ene-3,5-dione
MFCD00180244
Exo-N-hydroxy-7-oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboximide
(3aR,4S,7R,7aS)-2-Hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-epoxyisoindole-1,3-dione
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
384.8±52.0 °C at 760 mmHg
[ Melting Point ]:
194ºC (dec.)(lit.)
[ Molecular Formula ]:
C8H7NO4
[ Molecular Weight ]:
181.145
[ Flash Point ]:
186.5±30.7 °C
[ Exact Mass ]:
181.037506
[ PSA ]:
66.84000
[ LogP ]:
-1.47
[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C
[ Index of Refraction ]:
1.680
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37-S39
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2925190090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2925190090
[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
J. Comb. Chem. 12 , 655-658, (2010)
The parallel synthesis of O-aryloxyamines remains an unfulfilled need in the field of medicinal chemistry and fragment-based approaches. To fill this gap a solution-phase two-step process based on (1)...