5-Chloro-1,3-thiazol-2-amine hydrochloride (1:1)

Names

[ Name ]:
5-Chloro-1,3-thiazol-2-amine hydrochloride (1:1)

[Synonym ]:
5-Chloro-1,3-thiazol-2-amine hydrochloride (1:1)
2-Thiazolamine, 5-chloro-, hydrochloride (1:1)
MFCD00039006
EINECS 259-680-4
5-chloro-1,3-thiazol-2-amine,hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
260.5ºC at 760 mmHg

[ Melting Point ]:
164-167 °C (dec.)(lit.)

[ Molecular Formula ]:
C₃H₄Cl₂N₂S

[ Molecular Weight ]:
171.048

[ Flash Point ]:
111.3ºC

[ Exact Mass ]:
169.947220

[ PSA ]:
67.15000

[ LogP ]:
2.76190

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ1262800

CHEMICAL NAME :: 2-Thiazolamine, 5-chloro-, monohydrochloride

CAS REGISTRY NUMBER :: 55506-37-1

LAST UPDATED :: 199410

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C3-H3-Cl-N2-S.Cl-H

MOLECULAR WEIGHT :: 171.05

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Klebsiella pneumoniae

DOSE/DURATION :: 500 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 118,153,1983

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H317-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S26-S36/37

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
XJ1262800

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2934100090

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Effects of new ubiquinone-imidazo[2,1-b]thiazoles on mitochondrial complex I (NADH-ubiquinone reductase) and on mitochondrial permeability transition pore.

Bioorg. Med. Chem. 12 , 5525-5532, (2004)

In this work we describe the synthesis of a series of imidazo[2,1-b]thiazoles and 2,3-dihydroimidazo[2,1-b]thiazoles connected by means of a methylene bridge to CoQ(0). These compounds were tested as ...