Glycerol trimyristate

Names

[ CAS No. ]:
555-45-3

[ Name ]:
Glycerol trimyristate

[Synonym ]:
EINECS 209-099-7
UNII-18L31PSR28
1,2,3-Propanetriyl tritetradecanoate
Glyceryl tritetradecanoate
Myristic acid triglyceride
Tri-Myristin
trimyristoyl-sn-glycerol
1,2,3-Propanetriol tritetradecanoate
MFCD00036229
Dynasan 114
Tetradecanoic acid, 1,2,3-propanetriyl ester
2,3-di(tetradecanoyloxy)propyl tetradecanoate
Propane-1,2,3-triyl tritetradecanoate
1,2,3-Tritetradecanoylglycerol
Myristin, tri-
Myristin
Trimyristin
glycerol trimyristate
glyceryl trimyristate

Biological Activity

[Description]:

Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC50s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase

Research Areas >> Metabolic Disease

Signaling Pathways >> Neuronal Signaling >> AChE

[References]

[1]. Jaiswal P, et al. Enzyme Inhibition by Molluscicidal Components of Myristica fragrans Houtt. in the NervousTissue of Snail Lymnaea acuminata. Enzyme Res. 2010;2010:478746.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
703.5±27.0 °C at 760 mmHg

[ Melting Point ]:
56-57 °C(lit.)

[ Molecular Formula ]:
C₄₅H₈₆O₆

[ Molecular Weight ]:
723.161

[ Flash Point ]:
270.9±23.8 °C

[ Exact Mass ]:
722.642456

[ PSA ]:
78.90000

[ LogP ]:
18.89

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.464

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
-

[ HS Code ]:
2915900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Articles

A single step reversed-phase high performance liquid chromatography separation of polar and non-polar lipids.

J. Chromatogr. A. 1369 , 105-15, (2014)

This paper reports a simple chromatographic system to separate lipids classes as well as their molecular species. By the use of phenyl coated silica as stationary phase in combination with a simple mo...

Identification of lipid- and protein-based binders in paintings by direct on-plate wet chemistry and matrix-assisted laser desorption ionization mass spectrometry.

Anal. Bioanal. Chem 407(3) , 1015-22, (2015)

Direct on-target plate processing of small (ca. 100 μg) fragments of paint samples for MALDI-MS identification of lipid- and protein-based binders is described. Fragments were fixed on a conventional ...

Surface properties of artificial tear film lipid layers: effects of wax esters.

Invest. Ophthalmol. Vis. Sci. 55(7) , 4448-54, (2014)

The tear film lipid layer is believed to stabilize the tear film and to retard evaporation. Based on previous simple in vitro studies, the evidence for the latter property is scarce. In this study, we...