Herbicidin A
Names
[ CAS No. ]:
55353-31-6
[ Name ]:
Herbicidin A
Biological Activity
[Description]:
Herbicidin A is an adenosine-derived nucleoside antibiotic, but also is a herbicide against dicotyledonous plants. Herbicidin A can be isolated from Streptomyces scopuliridis M40[1][2].
[Related Catalog]:
[In Vitro]
Herbicidin A is the most extensively decorated herbicidin to date, which has a 5-hydroxytiglyl group at C8[1]. The precursors for herbicidin biosynthesis are D-glucose, D-ribose, Lisoleucine, and L-methionine[1]. Herbicidins are selective herbicide against dicotyledonous plants and inhibit the germination of Chinese cabbage and rice seeds[1]. Herbicidins can protect rice plants from leaf blight and also exhibit antialgal and antifungal activities[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C23H29N5O11
[ Molecular Weight ]:
551.50300
[ Exact Mass ]:
551.18600
[ PSA ]:
219.83000
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LV2630000
- CAS REGISTRY NUMBER :
- 55353-31-6
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C23-H29-N5-O11
- MOLECULAR WEIGHT :
- 551.57
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 29,863,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 5,305,1981