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Product Name: Herbicidin A
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Herbicidin A
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55353-31-6

55353-31-6 structure

55353-31-6 structure

Name: Herbicidin A
Chemical Name: Herbicidin-A
CAS Number: 55353-31-6
Molecular Formula: C₂₃H₂₉N₅O₁₁
Molecular Weight: 551.50300
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2016-11-07 05:08:42
Modify Date: 2024-01-05 16:25:05
Herbicidin A is an adenosine-derived nucleoside antibiotic, but also is a herbicide against dicotyledonous plants. Herbicidin A can be isolated from Streptomyces scopuliridis M40[1][2].

Name	Herbicidin-A

Description	Herbicidin A is an adenosine-derived nucleoside antibiotic, but also is a herbicide against dicotyledonous plants. Herbicidin A can be isolated from Streptomyces scopuliridis M40[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
In Vitro	Herbicidin A is the most extensively decorated herbicidin to date, which has a 5-hydroxytiglyl group at C8[1]. The precursors for herbicidin biosynthesis are D-glucose, D-ribose, Lisoleucine, and L-methionine[1]. Herbicidins are selective herbicide against dicotyledonous plants and inhibit the germination of Chinese cabbage and rice seeds[1]. Herbicidins can protect rice plants from leaf blight and also exhibit antialgal and antifungal activities[1].
References	[1]. Lin GM, et al. Identification and Interrogation of the Herbicidin Biosynthetic Gene Cluster: First Insight into the Biosynthesis of a Rare Undecose Nucleoside Antibiotic. J Am Chem Soc. 2017 Nov 22;139(46):16450-16453. [2]. Ha S, et al. Optimization of Herbicidin A Production in Submerged Culture of Streptomyces scopuliridis M40. J Microbiol Biotechnol. 2017 May 28;27(5):947-955.

Molecular Formula	C₂₃H₂₉N₅O₁₁
Molecular Weight	551.50300
Exact Mass	551.18600
PSA	219.83000

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LV2630000

CAS REGISTRY NUMBER :: 55353-31-6

LAST UPDATED :: 199206

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C23-H29-N5-O11

MOLECULAR WEIGHT :: 551.57

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 29,863,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 5,305,1981