4,4'-Bipyridine

Names

[ CAS No. ]:
553-26-4

[ Name ]:
4,4'-Bipyridine

[Synonym ]:
4,4'-Bipyridine
4,4-bipyridyl
g,g'-Dipyridyl
4, 4'-Dipyridine
4,4-bipyridine
EINECS 209-036-3
4,4,4'-DIPYRIDYL
4,4'-DIPYRIDINE
4,4′-bipyridyl
4,4'-BIPYRIDYL
4,4′-bipyridine
anhydrous 4,4'-bipyridyl
MFCD00006416
4,4-DIPYRIDYL
4,4'Bipyridinyl
4-(4-pyridyl)pyridine

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
304.8±0.0 °C at 760 mmHg

[ Melting Point ]:
109-112 °C(lit.)

[ Molecular Formula ]:
C₁₀H₈N₂

[ Molecular Weight ]:
156.184

[ Flash Point ]:
104.3±12.0 °C

[ Exact Mass ]:
156.068741

[ PSA ]:
25.78000

[ LogP ]:
1.20

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.581

[ Stability ]:
Stable. Incompatible with strong oxidizing agents, strong acids.

[ Water Solubility ]:
slightly soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DW1760000

CHEMICAL NAME :: 4,4'-Bipyridine

CAS REGISTRY NUMBER :: 553-26-4

BEILSTEIN REFERENCE NO. :: 0113176

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H8-N2

MOLECULAR WEIGHT :: 156.20

WISWESSER LINE NOTATION :: T6NJ D- DT6NJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 172 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 10,363,1982

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H319-H335

[ Precautionary Statements ]:
P261-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic

[ Risk Phrases ]:
R20/21;R25;R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
DW1760000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29333999

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Embedment of Ag(I)-organic frameworks into silica gels for microextraction of polybrominated diphenyl ethers in soils.

J. Chromatogr. A. 1383 , 18-24, (2015)

Three Ag(I)-organic frameworks, [Ag5(pydc)2(CN)]n, {[Ag4(pydc)2]CH3CN}n, and [Ag(4,4'-bpy)NO3]n, were synthesized and embedded into silica gels to form metal-organic-framework (MOF)-embedded gels for ...

Direct identification of on-bead peptides using surface-enhanced Raman spectroscopic barcoding system for high-throughput bioanalysis.

Sci. Rep. 5 , 10144, (2015)

Recently, preparation and screening of compound libraries remain one of the most challenging tasks in drug discovery, biomarker detection, and biomolecular profiling processes. So far, several distinc...

Synthesis, resolution, and absolute configuration of chiral 4,4'-bipyridines.

J. Org. Chem. 77(6) , 2579-83, (2012)

A chiral polyhalogenated 4,4'-bipyridine derivative is described allowing an easy access to a new family of chiral 4,4'-bipyridines by site-selective cross-coupling reactions. The absolute configurati...