4-Hydroxytryptamine creatinine sulfate

4-Hydroxytryptamine creatinine sulfate, a tryptamine derivative, is a neurotransmitter agonist[1].

Research Areas >> Neurological Disease

4-Hydroxytryptamine creatinine sulfate (uptake measurement: 20min; release measurement: 2 hours) effects the uptake and release of norepinephrine in mouse heart with a EC50 of 35μM/kg and 220 μM/kg, respectively[1]. Animal Model: 17-20 g Male albino mice[1] Dosage: Administration: intravenous injection (tail vein) Result: Effected the uptake and release of norepinephrine in mouse heart with a EC50 of 35μM/kg and 220 μM/kg, respectively.

[1]. [1]Creveling CR, et al. Dihydroxytryptamines: effects on noradrenergic function in mouse heart in vivo. Mol Pharmacol. 1975 Mar;11(2):211-22.