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Liquiritin

Names

[ CAS No. ]:
551-15-5

[ Name ]:
Liquiritin

[Synonym ]:
Liquiritoside
(2S)-7-hydroxy-2-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-2,3-dihydrochromen-4-one
Likviritin
4H-1-Benzopyran-4-one, 2-(4-(β-D-glucopyranosyloxy)phenyl)-2,3-dihydro-7-hydroxy-, (S)-
4',7-Dihydroxyflavanone 4'-(β-D-glucoside)
(S)-2-(4-(β-D-Glucopyranosyloxy)phenyl)-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2-[4-(β-D-glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-, (2S)-
4',7-Dihydroxyflavanone 4'-(β-D-glucopyranoside)
4-[(2S)-7-Hydroxy-4-oxo-3,4-dihydro-2H-chromen-2-yl]phenyl β-D-glucopyranoside
Liquiritin
liquiritigenin 4'-O-glucoside
Liquiritigenin-4'-O-glucoside

Biological Activity

[Description]:

Liquiritin is a flavonoid isolated from Glycyrrhiza, acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology
Research Areas >> Neurological Disease

[Target]

Liquiritin (100 µM) increases glucose-6-phosphate dehydrogenase expression on B65 neuroblastoma cells[1].


[References]

[1]. Nakatani Y, et al. Neuroprotective effect of liquiritin as an antioxidant via an increase in glucose-6-phosphate dehydrogenase expression on B65 neuroblastoma cells. Eur J Pharmacol. 2017 Nov 15;815:381-390.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
746.8±60.0 °C at 760 mmHg

[ Melting Point ]:
212 °C

[ Molecular Formula ]:
C21H22O9

[ Molecular Weight ]:
418.39

[ Flash Point ]:
265.9±26.4 °C

[ Exact Mass ]:
418.126373

[ PSA ]:
145.91000

[ LogP ]:
0.61

[ Vapour Pressure ]:
0.0±2.6 mmHg at 25°C

[ Index of Refraction ]:
1.670

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
29389090

Precursor & DownStream


Related Compounds

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