PD 334581

Names

[ CAS No. ]:
548756-68-9

[ Name ]:
PD 334581

Biological Activity

[Description]:

PD-334581 is a MEK1 inhibitor[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> MAPK/ERK Pathway >> MEK

[Target]

MEK1

[References]

[1]. Ohren JF, et al. Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition. Nat Struct Mol Biol. 2004 Dec;11(12):1192-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₉F₃IN₅O₂

[ Molecular Weight ]:
545.29700

[ Exact Mass ]:
545.05400

[ PSA ]:
75.45000

[ LogP ]:
4.33010

Related Compounds

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