Protohypericin

Names

[ CAS No. ]:
548-03-8

[ Name ]:
Protohypericin

[Synonym ]:
1,3,4,6,8,15-Hexahydroxy-10,13-dimethyl-dibenzo[a,o]perylen-7,16-dion
Dibenzo(a,o)perylene-7,16-dione,1,3,4,6,8,15-hexahydroxy-10,11-dimethyl
1,3,4,6,8,15-hexahydroxy-10,13-dimethyl-dibenzo[a,o]perylene-7,16-dione

Biological Activity

[Description]:

Protohypericin is a naturally occurring naphthodianthrone derived from plant Hypericum perforatum. Radioiodinated protohypericin is used in Tumor necrosis targeted radiotherapy[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Baugh SF. Simultaneous determination of protopseudohypericin, pseudohypericin, protohypericin, and hypericin without light exposure. J AOAC Int. 2005 Nov-Dec;88(6):1607-12.

[2]. Liu X, et al. Tumor necrosis targeted radiotherapy of non-small cell lung cancer using radioiodinated protohypericin in a mouse model. Oncotarget. 2015 Sep 22;6(28):26400-10.

Chemical & Physical Properties

[ Density]:
1.736g/cm3

[ Boiling Point ]:
954.3ºC at 760mmHg

[ Molecular Formula ]:
C₃₀H₁₈O₈

[ Molecular Weight ]:
476.47600

[ Flash Point ]:
544.7ºC

[ Exact Mass ]:
476.12600

[ PSA ]:
121.38000

[ LogP ]:
6.89400

Safety Information

[ HS Code ]:
2914400090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914400090

[ Summary ]:
2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.