5β-cholanoic acid

Names

[ CAS No. ]:
546-18-9

[ Name ]:
5β-cholanoic acid

[Synonym ]:
(5β)-Cholan-24-oic acid
5b-Cholan-24-oic Acid
5beta-Cholanoic acid
Cholan-24-oic acid, (5β)-
Ursocholanic acid
5beta-Cholan-24-oic acid
5β-cholan-24-oic acid
(4R)-4-[(5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
5β-cholanic acid
MFCD00065904
Cholanoic acid
5beta-Cholanic acid
(5b,17b)-g-Methylandrostane-17-butanoic acid
CHOLANIC ACID, (5β)-

Biological Activity

[Description]:

5β-Cholanic acid can be used for 5β-Cholanic acid derivatives synthesis[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Weizhi Wang, et al. Improved oral delivery of insulin by PLGA nanoparticles coated with 5 β-cholanic acid conjugated glycol chitosan. Biomed Mater. 2021 Oct 12;16(6).

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
473.6±13.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₄H₄₀O₂

[ Molecular Weight ]:
360.573

[ Flash Point ]:
208.7±11.2 °C

[ Exact Mass ]:
360.302826

[ PSA ]:
37.30000

[ LogP ]:
8.75

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.514

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

An efficient synthesis of 4 beta- and 6 alpha-hydroxylated bile acids.

Steroids 58(2) , 52-8, (1993)

An efficient method for the preparation of 4 beta- and 6 alpha-hydroxylated bile acids has been developed. It involved a highly stereoselective acetoxylation at the 4 beta and 6 alpha positions of 3- ...

Calcium- and voltage-gated potassium (BK) channel activators in the 5β-cholanic acid-3α-ol analogue series with modifications in the lateral chain.

ChemMedChem 7(10) , 1784-92, (2012)

Large conductance, calcium- and voltage-gated potassium (BK) channels regulate various physiological processes and represent an attractive target for drug discovery. Numerous BK channel activators are...

Cholanic acids determined in commercial drugs by means of a new ISFET device.

J. Pharm. Biomed. Anal. 11(11-12) , 1207-14, (1993)

An ISFET device selective for cholanic acids, based on a PVC-sebacate membrane, containing benzyldimethylcetylammoniumcholate as exchanger, has been prepared, characterized and applied to the determin...