N,N′-2,6-PYRIDINEDIYLBISACETAMIDE
Names
[ CAS No. ]:
5441-02-1
[ Name ]:
N,N′-2,6-PYRIDINEDIYLBISACETAMIDE
[Synonym ]:
Pyridine,2,6-diacetamido
2,6-di(acetylamino)pyridine
Acetamide,N,N'-2,6-pyridinediylbis
N,N'-(pyridine-2,6-diyl)diacetamide
SN 3,363
N,N'-pyridine-2,6-diylbis(acetylamide)
N,N'-2,6-Pyridinediylbisacetamide
2,6-N,N-Diacetyldiaminopyridine
2,6-Diacetamidopyridine
2,6-bis(methylcarbonylamino)pyridine
Chemical & Physical Properties
[ Molecular Formula ]:
C9H11N3O2
[ Molecular Weight ]:
193.20300
[ Exact Mass ]:
193.08500
[ PSA ]:
71.09000
[ LogP ]:
1.14440
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AC7849500
- CHEMICAL NAME :
- Acetamide, N,N'-2,6-pyridinediylbis-
- CAS REGISTRY NUMBER :
- 5441-02-1
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C9-H11-N3-O2
- MOLECULAR WEIGHT :
- 193.23
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 375 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,235,1946 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 46800 mg/kg/30D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- REFERENCE :
- 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,235,1946
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 600 mg/kg/6D-I
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Kidney, Ureter, Bladder - hematuria Blood - changes in erythrocyte (RBC) count
- REFERENCE :
- 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,235,1946
Safety Information
[ HS Code ]:
2933399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%