3-Chloro-N,N-dimethylpropan-1-amine hydrochloride

Names

[ Name ]:
3-Chloro-N,N-dimethylpropan-1-amine hydrochloride

[Synonym ]:
3-dimethylaminoprop-1-yl chloride hydrochloride
Propylamine, 3-chloro-N,N-dimethyl-, hydrochloride (8CI)
3-Chloro-N,N-dimethylpropylamine
3-Dimethylamino-1-propyl chloride hydrochloride
3-Chloro-N,N-dimethyl-1-propanamine hydrochloride (1:1)
3-Chloro-N,N-dimethylpropylamine Hydrochloride
3-chloro-N,N-dimethylaminopropane hydrochloride
2-DIMETHYLAMINO ISOPROPYL CHLORIDE HCL
N,N-dimethylamino-3-chloropropane hydrochloride
MFCD00012534
1-Propanamine, 3-chloro-N,N-dimethyl-, hydrochloride (1:1)
EINECS 224-971-7
3-Dimethylaminopropyl chloride hydrochloride
3-Chloro-N,N-dimethylpropan-1-amine hydrochloride (1:1)
3-(Dimethylamino)propyl Chloride Hydrochloride
2-CHLOROPROPYLDIMETHYLAMMONIUM CHLORIDE
2-DMPC
N,N-dimethyl-3-aminopropyl chloride hydrochloride
3-Chloro-N,N-dimethylpropan-1-amine hydrochloride
DMPC

Biological Activity

[Description]:

3-Chloro-N,N-dimethylpropan-1-amine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

3-Chloro-N,N-dimethylpropan-1-amine hydrochloride 主要用作医药中间体，用于合成多种药物和农药中间体，也用作照相化学中间体，用作酶和生化试剂其他研究。它显示诱变活性。

Chemical & Physical Properties

[ Boiling Point ]:
130.7ºC at 760mmHg

[ Melting Point ]:
187-190 °C(lit.)

[ Molecular Formula ]:
C₅H₁₃Cl₂N

[ Molecular Weight ]:
158.07

[ Flash Point ]:
32.8ºC

[ Exact Mass ]:
157.042511

[ PSA ]:
3.24000

[ LogP ]:
1.97890

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UI0209950

CHEMICAL NAME :: 1-Propylamine, 3-chloro-N,N-dimethyl-, hydrochloride

CAS REGISTRY NUMBER :: 5407-04-5

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C5-H12-Cl-N.Cl-H

MOLECULAR WEIGHT :: 158.09

WISWESSER LINE NOTATION :: G3N1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 mg/L

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,33,1981

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38;R52/53

[ Safety Phrases ]:
S26-S61-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
TY1225000

[ HS Code ]:
2921199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Preparation

Customs

[ HS Code ]: 2921199090

[ Summary ]:
2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Interaction of tricyclic drug analogs with synaptic plasma membranes: structure-mechanism relationships in inhibition of neuronal Na+/K(+)-ATPase activity.

Mol. Pharmacol. 44(1) , 129-41, (1993)

Perturbations of rat brain synaptic plasma membrane (SPM) bilayer structure and Na+/K(+)-ATPase activity were correlated for drugs that are structurally related and exhibit similar toxicological side ...