7-Amino-3-chloro cephalosporanic acid

Names

[ Name ]:
7-Amino-3-chloro cephalosporanic acid

[Synonym ]:
7-Amino-3-chlorocephalosporanic Acid
5-Thia-1-azabicyclo[4.2.0]oct-2-en-7-aminium, 2-carboxy-3-chloro-8-oxo-, inner salt, (6R,7R)-
3-Chloro-7-amino-3-cephem-4-carboxylic Acid
(6R-trans)-7-amino-3-chloro-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
MFCD03650764
(6R,7R)-7-Ammonio-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-Amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
EINECS 258-907-4
7-ACCA

Biological Activity

[Description]:

7-Amino-3-chloro cephalosporanic acid (7-ACCA) is an important intermediate for the synthesis of the second generation cephalosporins Cefaclor (HY-B0198)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Xiaoling Wu, et al. Improving Biocatalysis of Cefaclor With Penicillin Acylase Immobilized on Magnetic Nanocrystalline Cellulose in Deep Eutectic Solvent Based Co-Solvent. Bioresour Technol. 2019 Sep;288:121548.

Chemical & Physical Properties

[ Density]:
1.81g/cm3

[ Boiling Point ]:
498.9±45.0 °C at 760 mmHg

[ Melting Point ]:
>180°C (分解)

[ Molecular Formula ]:
C₇H₇ClN₂O₃S

[ Molecular Weight ]:
234.660

[ Flash Point ]:
255.5±28.7 °C

[ Exact Mass ]:
233.986588

[ PSA ]:
108.93000

[ LogP ]:
-0.80

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.735

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2934996000

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934996000

[ Summary ]:
2934996000. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:6.0%. General tariff:20.0%