TROPONE

Names

[ CAS No. ]:
539-80-0

[ Name ]:
TROPONE

[Synonym ]:
2,4,6-CYCLOHEPTATRIEN-1-ONE
2,4,6-cycloheptatrienone
Tropone
cyclohepta-2,4,6-trienone
2,4,6-cycloheptatrieneone
cycloheptatrienone
1-cyclohepta-2,4,6-trienone
MFCD00014331
N-phenyl-2-azulenylmethylene
EINECS 208-725-6

Biological Activity

[Description]:

Tropone is a building block in the chemical synthesis[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Ying Duan, et al. Bacterial Tropone Natural Products and Derivatives: Overview of their Biosynthesis, Bioactivities, Ecological Role and Biotechnological Potential. Chembiochem. 2020 Sep 1;21(17):2384-2407.

Chemical & Physical Properties

[ Density]:
1.094

[ Boiling Point ]:
113ºC (15 torr)

[ Melting Point ]:
-7ºC

[ Molecular Formula ]:
C₇H₆O

[ Molecular Weight ]:
106.12200

[ Flash Point ]:
85.6ºC

[ Exact Mass ]:
106.04200

[ PSA ]:
17.07000

[ LogP ]:
1.04680

[ Index of Refraction ]:
n20/D 1.615(lit.)

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2914299000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914299000

[ Summary ]:
2914299000. other cyclanic, cyclenic or cyclotherpenic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Benzo[cd]azulene skeleton: azulene, heptafulvene, and tropone derivatives.

Org. Lett. 11(23) , 5363-5, (2009)

Due to our interest in protein kinase modulating compounds, we developed syntheses for benzo[cd]azulenes. By using very common catalysts and reagents, such as t-BuOK, HCl, and mCPBA, the commercially ...

Tropylium tetrafluoroborate, a novel substrate for aldehyde oxidase.

Biochem. Biophys. Res. Commun. 140(2) , 609-15, (1986)

The stabilized carbonium ion salt, tropylium tetrafluoroborate, was oxidized to tropone (cycloheptatrienone) by rabbit liver aldehyde oxidase but not by the closely related molybdenum hydroxylase, xan...

Potential of Piperazinylalkylester Prodrugs of 6-Methoxy-2-Naphthylacetic Acid (6-MNA) for Percutaneous Drug Delivery.

Z. Naturforsch., C, J. Biosci. 59(3-4) , 184-6, (2004)

Piperazinylalkyl ester prodrugs (4a-5d) of 6-methoxy-2-naphthylacetic acid (6-MNA) (1) were synthesized and evaluated in vitro for the purpose of percutaneous drug delivery. These ionizable prodrugs e...