Furylacrylic acid
Names
[ CAS No. ]:
539-47-9
[ Name ]:
Furylacrylic acid
[Synonym ]:
2-Propenoic acid, 3-(2-furanyl)-, (2E)-
Furfurylidene Acetic Acid
β-(2-Furyl)acrylic acid
2-Propenoic acid, 3- (2-furanyl)-
2-Propenoic acid, 3-(2-furanyl)-
EINECS 208-718-8
2-Furanacrylic Acid
b-2-Furylacrylic Acid
(2E)-3-(2-Furyl)acrylic acid
MFCD00003257
3-(Furan-2-yl)acrylic acid
3-(2-Furyl)acrylic Acid
Furylacrylic acid
Nalfurafine Impurity 7
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
286.0±0.0 °C at 760 mmHg
[ Melting Point ]:
139-141 °C(lit.)
[ Molecular Formula ]:
C7H6O3
[ Molecular Weight ]:
138.121
[ Flash Point ]:
106.8±20.4 °C
[ Exact Mass ]:
138.031693
[ PSA ]:
50.44000
[ LogP ]:
2.03
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.582
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LT8560000
- CHEMICAL NAME :
- 2-Furanacrylic acid
- CAS REGISTRY NUMBER :
- 539-47-9
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C7-H6-O3
- MOLECULAR WEIGHT :
- 138.13
- WISWESSER LINE NOTATION :
- T5OJ B1U1VQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 276 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 10 ug/plate
- REFERENCE :
- JOPHDQ Journal of Pharmacobio-Dynamics. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1978- Volume(issue)/page/year: 1,15,1978
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
LT8560000
[ HS Code ]:
29321900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 29321900
Articles
Biochemistry 22(1) , 103-10, (1983)
Furanacryloyl-Phe-Gly-Gly has been shown to be a convenient substrate for angiotensin converting enzyme (dipeptidyl carboxypeptidase, EC 3.4.15.1). A detailed kinetic analysis of the hydrolysis of thi...
Activation of angiotensin converting enzyme by monovalent anions.Biochemistry 22(1) , 110-6, (1983)
The angiotensin converting enzyme catalyzed hydrolysis of furanacryloyl-Phe-Gly-Gly is activated by monovalent anions in the order C1- greater than Br- greater than F- greater than NO3- greater than C...
Esters of 2-furanacrylic acid.J. Am. Chem. Soc. 69(2) , 460, (1947)