rac 4-Hydroxy-3-methoxyphenylethylene Glycol

Names

[ CAS No. ]:
534-82-7

[ Name ]:
rac 4-Hydroxy-3-methoxyphenylethylene Glycol

[Synonym ]:
4-hydroxy-3-methoxy-d3-phenylethylene glycol

Biological Activity

[Description]:

3-Methoxy-4-hydroxyphenylglycol (HMPG) is a metabolite of norepinephrine degradation in the brain. 3-Methoxy-4-hydroxyphenylglycol is an indicators of central nervous system noradrenergic activity. 3-Methoxy-4-hydroxyphenylglycol can be used for research of depression, chronic schizophrenia, etc[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[Target]

Human Endogenous Metabolite

[References]

[1]. Lambert GW, et al. Regional origins of 3-methoxy-4-hydroxyphenylglycol in plasma: effects of chronic sympathetic nervous activation and denervation, and acute reflex sympathetic stimulation. J Auton Nerv Syst. 1995 Nov 6;55(3):169-78.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₂O₄

[ Molecular Weight ]:
184.19

[ Exact Mass ]:
187.09200

[ PSA ]:
69.92000

[ LogP ]:
0.42650

Safety Information

[ HS Code ]:
2909499000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2909499000

[ Summary ]:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%